Lessons Learned from Two Research Studies Enrolling Underrepresented Patients with Ventricular Assist Devices and their Family Caregivers.

Given the continued challenges and barriers of recruiting and retaining underrepresented groups in cardiovascular studies, this paper aims to describe successful recruitment strategies used by two related ventricular assist device (VAD) studies. The two exemplar studies focused on understanding how adults with a VAD and their family caregivers discuss, reflect upon, and act on their personal values. To recruit a more representative and diverse sample reflective of the substantial Black population receiving care at the local, academic hospital outpatient clinic, we developed multipronged recruitment strategies for a convergent mixed methods study (Study 1) and sequential explanatory mixed methods study (Study 2).

The portrayal of panic-buying and stockpiling in English newspapers during Covid, a mixed-method content analysis.

Panic-buying and stockpiling during Covid disrupted the supply chain, causing food shortages and impacting the vulnerable. The government faced criticism for its lack of food system resilience, poor communications planning, and reliance on retailers. The British media frequently reported on panic-buying during early lockdown stages in 2020 and throughout Covid.

Congestion Enriches Intra-hepatic macrophages Through Reverse Zonation of CXCL9 in Liver Sinusoidal Endothelial Cells.

Background & Aims: Congestion alters the microenvironment of the liver sinusoid along the portal-central axis. We studied spatial changes in immune cells in the sinusoid that contribute to congestive fibrosis and portal hypertension (PHTN).

Methods: To visualize the distribution of immune cells in congestive hepatopathy (CH), we performed imaging mass cytometry (IMC) on liver tissue from patients with CH, Fontan-associated liver disease (FALD), and controls.

A Clinical Practice-Based Comparison of Conventional and Individualized Dosing Strategies for Therapeutic Enoxaparin.

To understand differences in anti-factor-Xa levels produced by two different dosing strategies (conventional and individualized) for therapeutic enoxaparin in a cohort of hospital inpatients. A multicenter, retrospective cohort study over a two- and a half-year period for inpatients with stable renal function and on therapeutic enoxaparin. Anti-factor-Xa levels were taken 3-5 h after enoxaparin administration and a minimum of 48 h of dosing.

Cultural adaptation of ENABLE (Educate, Nurture, Advise, Before Life Ends) an early palliative care model for Iranian patients with heart failure and their caregivers: a qualitative study protocol.

Background: ENABLE (Educate, Nurture, Advise, Before Life Ends) is a model of nurse-led, early palliative care that was originally developed for U.S. patients with advanced cancer and their family caregivers and then adapted for patients with heart failure.