[The study of influence of acoustic oscillations on the immunogenesis].

It was found out, that immunomodulative action of low frequency acoustic oscillations (LFAO) is mediated in mice by enhancement or decreasing of distinct stages of immunogenesis. Exposure to this factor at intensity of 80 dB varied number of cells in lymphoid organs, enhanced cell proliferation, improved cooperative interaction of thymocytes and bone marrow cells in immune response, caused increase of allogenic stem cells inactivation. On the contrary, exposure to LFAO at the acoustic pressure of 130 dB caused alternative effects, as inhibition of immunocompetent cells in interaction.

[Perfection of methodical approaches to designing vaccines against tick-borne encephalitis].

The protective properties of experimental vaccine against tick-borne encephalitis (TBE) were studied. The vaccine was prepared by conjugating colloid gold with soluble TBE antigen. The protective properties of experimental and commercial vaccines were compared by the mean survival time and protection coefficients after one and three vaccinations of mice infected in doses of 100,000 and 10,000 LD50.

[Area and natural reservoirs of hemorrhagic fever virus with kidney syndrome in the Far East of the USSR].

Lungs of 9127 small mammals of 17 species trapped in Khabarovsk region, Magadan, Amur, and Sakhalin regions in 1982-1987 were examined, among them 11 species are reservoirs of HFRS virus. Most frequently infected are striped field mice and Japanese field mice, red voles and large-toothed red-backed voles which are the dominant species of the appropriate landscape formations. Circulation of two HFRS virus serotypes among small mammals was demonstrated.

[Effect of purified sewage on the composition of carcinogenic polycyclic aromatic hydrocarbons in the soil and vegetation].

Concentrations of benz(a)pyrene (BP) and 15 other polycyclic aromatic hydrocarbons (PAH) in soil with forage plants (lucerne) irrigated by biologically purified mixed domestic and industrial (coke-chemical) sewage from collection pond did not exceed those in control soil (irrigated by relatively clean fresh water) and were lower than in nonirrigated one, which is due, probably, to PAH oxidation by soil-proper microflora activated in humid soil polluted by PAH. BP content in control and experimental samples of lucerne coincide within +/- 25% limits.