Quality-of-Life Measurement in Epidermolysis Bullosa. Position Statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient-Oriented Outcomes and External Experts.

In this paper, the European Academy of Dermatology and Venereology (EADV) Task Force on Quality of Life (QoL) and Patient-Oriented Outcomes presents its position statements on health-related (HR) QoL assessment in epidermolysis bullosa (EB). The EADV TF on QoL and Patient-Oriented Outcomes recommends the use of the EB-specific instrument QOLEB in patients over the age of 10 years and, in addition to the QOLEB, the use of iscorEB-p in moderate-to-severe EB; the IntoDermQoL proxy instrument with its EB-specific module should be used in children aged under 5 years. The EB-specific instrument iscorEB-p, and the dermatology-specific instrument CDLQI may measure HRQoL in children with EB aged from 5 to 10 years.

ARTIFICIAL TERMINATION OF PREGNANCY IN UKRAINE: BIOETHICAL, PHILOSOPHICAL AND RELIGIOUS ASPECTS.

Objective: The aim: Is to study the levels of influence of the Christian spiritual tradition on the attitude of medical students to abortion, which necessitated a comparative analysis of Christian ethics and the main approaches of secular bioethics regarding artificial termination of pregnancy; analysis of the results of sociological research taking into account the peculiarities of religious self-identification of medical students.

Patients And Methods: Materials and methods: The complex nature of the studied issue necessitated the application of interdisciplinary approaches, philosophical, general scientific and special sociological methods of collecting, processing and analyzing information. Certain differences between Christian moral guidelines and attitudes towards artificial termination of pregnancy were found in a questionnaire study conducted by a sociological group of the Bogomolets National Medical University (hereinafter - NMU) in 2020.

[Hemocoagulation disorders in patients with acute pancreatitis].

62 patients with acute pancreatitis (AP) were examined in order to determine hemocoagulation disorders. The obtained results showed that the patients developed the consumptive coagulopathy with high levels of D-dimer, activation and exhaustion of antithrombin III (AT III). The development of hemocoagulation disturbances in patients with severe AP was confirmed through decrease of activity of AT III up to 68% and high level of D-dimer>693 ng/ml.

[Prognosis of the disease severity in patients with acute pancreatitis].

Estimation of the severity state in patient, suffering an acute pancreatitis, while admitting him into a hospital, constitutes a significant part of diagnosis and complex treatment. Application of a highly accurate scales and markers, which are used to prognosticate the disease course severity and to determine the inflammation grade, may influence the results of complex treatment of the patients. In the investigation a high diagnostic accuracy in prognosis of an acute pancreatitis course severity was noted for APACHE II scale (24 hours) and Ranson scale (48 hours).