Identification of Myeloid Protein Kinase C - Epsilon as a Novel Atheroprotective Gene.

Protein Kinase C - epsilon (PKCɛ) is involved in diverse cellular processes such as migration, growth, differentiation, and survival. Public geneset analysis of human atherosclerotic plaque tissue revealed that PKCɛ expression is inversely correlated with plaque size and vulnerability. Similarly, peritoneal macrophages (MØ) from hypercholesterolemic mice have significantly lower PKCɛ expression.

Scholars in Health Equity: A Program of Structured Physician Faculty Development.

Background: Structured faculty development programs focused on integrating health equity into medical education curricula remain limited.

Aim: To describe an interdisciplinary faculty development program grounded in adult learning theory and to assess its impact on participants' professional growth.

Setting And Participants: Twenty-one faculty members across six academic-affiliated health systems.

Treatment-induced ripple effect: a systematic review exploring the abscopal phenomenon in Glioblastoma multiforme.

Purpose: This systematic review aimed to collate and synthesize the available literature on the abscopal effect in Glioblastoma multiforme (GBM) neoplasms, focusing on the reported biochemical mechanisms driving the abscopal effect.

Methods: A systematic search was conducted in PubMed, Cochrane Database of Systematic Reviews, and Epistemonikos from inception to May 1, 2023. Studies exploring the abscopal effect in GBM were included.

Parasite infestations and infections of non-traditional pets and wild mammals: diagnosis and treatment.

Little is known about parasites in wild mammals kept as pets. For this study, fecal and skin/fur samples and ectoparasites from 55 wild and pet mammals attended at a veterinary clinic were evaluated. Opossums (Didelphis albiventris and Didelphis aurita) were parasitized by helminths (Aspidodera sp.

Educational technology to empower patients as participants in their care.

Objectives: to build and validate an educational technology to empower patients as participants in their own care.

Methods: methodological study to develop an educational technology based on the elaboration, validation, and evaluation that were carried out in five stages at a teaching hospital in Amazonas. The study was carried out from 2019 to 2022, with the participation of 19 judges specialized in patient safety and 72 patients admitted to the hospital's medical and surgical clinics, the study setting.