Zh Vyssh Nerv Deiat Im I P Pavlova
March 1979
In experiments on alert rabbits it was shown that during the first blinking conditioned reflex to a sound, a slow negative potential appears in response to the conditioned signal in the auditory area of the cortex. At the cellular level, this correlates with the formation of polysensory neurone activity accompanied by a small increase in its action potential duration (generalization of excitation, depolarization). During stabilization of the reflex, its specialization, coordinative inhibition of other central responses related to narrowing of receptive areas, --a slow positive potential is evoked in EEG by the conditioned stimulus.
View Article and Find Full Text PDFFiziol Zh SSSR Im I M Sechenova
June 1975
Extracellular application of 5--10 mM/L etimizol exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude. The effect was reversible and depended upon the etimizol concentration and the initial functional state of neurons. Etimizol is supposed to decrease the K-+ permeability of neurons' membrane during action potential.
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