Publications by authors named "R S Mello"

Article Synopsis
  • Arketamine (R-ketamine) has shown potential for prolonged antidepressant effects and better safety compared to esketamine (S-ketamine), though it has been less studied.
  • A review of 20 studies with 410 subjects indicated arketamine's effectiveness for pain management and depression, but many studies were small and informal.
  • While arketamine generally has a favorable safety profile, more substantial research is needed to better understand its therapeutic potential and proper clinical usage.
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A catalog of Ulidiidae, picture-winged flies, from Chile is provided. Included are all valid names and synonyms for the 16 species and nine genera known from Chile, including information about name, author, year of publication, page number, type species, type locality, and references. Euxesta Loew is the more species richness genus in Chile, with five species, followed by Ceroxys Macquart, with two species.

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A review of Senopterina Macquart, 1835, a Nearctic and Neotropical genus with 21 species, is presented. Senopterina brevipes (Fabricius, 1805), the type species of the genus, and S. macularis (Fabricius, 1805), are redescribed.

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Introduction: Advanced malignant melanoma is a very aggressive disease, historically with poor prognosis before the new advances with immunotherapy and targeted therapies that have changed the standard of care, especially in cutaneous melanoma. Peru has aggressive features such as higher rates of acral lentiginous melanoma (ALM) subtype with historically shorter survival.

Methods: This study describes Peruvian patients with advanced melanoma treated with immunotherapy (nivolumab) in two oncological institutions (public and private), including the discussion of the impact on overall survival (OS) divided by subtype (with incidence in ALM histology) and potential biomarkers that could be related to prognosis.

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Introduction: Breast Cancer (BC) is one of the most diagnosed malignancies among women and the second leading cause of cancer related death in North America. Triple Negative BC (TNBC), one of the most severe subtypes of BC, is extremely aggressive and has a higher chance of occurrence in women under 50 years of age. Due to a lack of regular mammographic testing in women under 50, many individuals with TNBC are diagnosed late which can decrease their survival rate.

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