Is liquid-based pap testing affected by water-based lubricant?

Objective: To estimate the effect of water-based lubricant on the liquid-based Pap test.

Methods: Two hundred women each had 2 simultaneous Pap test collections. One specimen was randomly contaminated with 0.

Three subpopulations of fast axonally transported retinal ganglion cell proteins are differentially trafficked in the rat optic pathway.

Post-Golgi trafficking of the major fast axonally transported (FT) proteins was investigated in the rat optic pathway. Following intra-ocular injection of 35S-methionine, radiolabeled FT proteins in the optic tract (OT) and superior colliculus (SC) were analyzed by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and fluorography. Twenty FT proteins, including a known plasma membrane protein (SNAP-25) and synaptic vesicle protein (synaptobrevin-2), displayed consistent 2D-PAGE migration behavior and were chosen for densitometric quantitative analysis.