Publications by authors named "R S Joosen"
Background: Pulmonary artery (PA) stenosis is common after arterial switch operation (ASO) for transposition of the great arteries (TGA). Differences between balloon angioplasty (BA) and stents on right ventricular (RV) and PA pressures are not well studied.
Objectives: The purpose of this study was to analyze percutaneous PA interventions' frequency after ASO, complications, and the effects of BA and stents on RV and PA pressures.
Background: Branch pulmonary artery (PA) stenosis is one of the most common indications for percutaneous interventions in patients with transposition of the great arteries (TGA), tetralogy of Fallot (ToF), and truncus arteriosus (TA). However, the effects of percutaneous branch PA interventions on exercise capacity remains largely unknown. In addition, there is no consensus about the optimal timing of the intervention for asymptomatic patients according to international guidelines.
View Article and Find Full Text PDFMulti-parent populations (MPPs) are attractive for genetic and breeding studies because they combine genetic diversity with an easy-to-control population structure. Most methods for mapping QTLs in MPPs focus on the detection of QTLs in single environments. Little attention has been given to mapping QTLs in multienvironment trials (METs) and to detecting and modeling QTL-by-environment interactions (QEIs).
View Article and Find Full Text PDFArticle Synopsis
- The study assessed the long-term clinical outcomes of patients who underwent an arterial switch operation (ASO) for transposition of the great arteries (TGA), highlighting a growing patient population.
- Findings indicated that at age 35, the survival rate was high at 93%, but a significant percentage (36%) required re-interventions, particularly affecting the right ventricular outflow tract.
- The research concluded that while survival rates are favorable, continuous monitoring and potential interventions are necessary throughout the patients' lives, with specific subtypes of TGA presenting higher risks for complications.
Background: Unilateral pulmonary artery (PA) stenosis is common in the transposition of the great arteries (TGA) after arterial switch operation (ASO) but the effects on the right ventricle (RV) remain unclear.
Aims: To assess the effects of unilateral PA stenosis on RV afterload and function in pediatric patients with TGA-ASO.
Methods: In this retrospective study, eight TGA patients with unilateral PA stenosis underwent heart catheterization and cardiac magnetic resonance (CMR) imaging.