Unilateral biportal endoscopy: review and detailed surgical approach to extraforaminal approach.

Foraminal and extraforaminal lumbar disc herniations are common sources of pain and disability. Classic surgical treatments, such as open approach through Witsel technique, often involve resection of the superior articular process to decompress the foraminal space. Unilateral biportal endoscopy (UBE) has emerged as a minimally invasive alternative, providing enhanced visualization and precision while minimizing soft tissue damage.

ELECTROCHEMOTHERAPY WITH CISPLATIN FOR THE TREATMENT OF A NON-OPERABLE ORAL SQUAMOUS CELL CARCINOMA IN A LOWLAND TAPIR ().

Squamous cell carcinoma (SCC) is a malignant epidermal tumor. Biologic behavior and metastasis rate vary according to species and tumor location. The goal of this study was to report the occurrence and behavior of an oral SCC in a treated with electrochemotherapy.

Controlling Protein Immobilization over Poly(3-hydroxybutyrate) Microparticles Using Substrate Binding Domain from PHA Depolymerase.

Biointerface decoration with ligands is a crucial requirement to modulate biodistribution, increase half-life, and provide navigation control for targeted micro- or nanostructured systems. To better control the process of ligand functionalization over three-dimensional (3D) polyester surfaces, we report the characterization of hybrid proteins developed to enhance the anchoring efficiency over polymeric surfaces and preserve optimal spatial orientation: sfGFP, mRFP1, and the RBD proteins were attached to a polyester substrate binding domain (SBD) formed by the C-terminus region of PHA depolymerase. The binding ability was evaluated over poly(3-hydroxybutyrate) (PHB) microparticles (MP) and two-dimensional (2D) surfaces.

Travel-associated international spread of Oropouche virus beyond the Amazon.

Oropouche virus (OROV), first detected in Trinidad and Tobago in 1955, was historically confined to the Brazilian Amazon Basin. However, since late 2022, an increasing number of OROV cases have been reported across various regions ofBrazilas well as in urban centers in Bolivia, Ecuador, Guyana, Colombia, Cuba, Panama and Peru. In collaboration with Central Public Health Laboratories across Brazil, we integrated epidemiological metadata with genomic analyses from recent cases, generating 133 whole-genome sequences covering the virus's three genomic segments (L, M, and S).

Development of carrageenan-based emulsion gel as a vehicle to transport xylo-oligosaccharides and its functional properties.

Xylo-oligosaccharides (XOSs) are prebiotic compounds that promote the growth of beneficial microorganisms in the intestinal tract and show resistance to enzymatic digestion, which makes them ideal for use as ingredients in healthy foods. This study presents the development of a new prebiotic and antioxidant carrageenan-based emulsion gel (EG) as a vehicle to transport XOSs obtained from sugarcane bagasse. The aim of developing the EG is its future potential application as a saturated fat replacement ingredient in food products with added functional properties (antioxidant and prebiotic).