Radiologic evaluation in the diagnosis of diplopia due to unilateral accessory extraocular muscle.

This case report details a case of a 52-year-old female with a history of diplopia and an elevation deficit in her right eye. Initially misdiagnosed as an atavistic retractor bulbi muscle in 2005 via MRI, symptoms persisted despite surgical excision. Follow-up MRI in 2023 confirmed no changes, ruling out other causes like nerve palsy or schwannoma, and ultimately guiding diagnosis towards an accessory extraocular muscle.

Patient-reported disease control versus overall symptom severity as global metrics of chronic rhinosinusitis disease status.

Background: Overall symptom severity (OSS) and patient-reported chronic rhinosinusitis (CRS) control are global measures of CRS identified as consensus, essential criteria for CRS disease control assessment. We sought to determine the functional relationship between these two metrics.

Methods: Using an international multicenter mixed-methods design, 260 CRS patients were recruited.

Overall symptom severity as a patient-reported outcome measure for chronic rhinosinusitis: what it reflects and how to measure it.

Background: The objective of this study was to identify how - and to what extent - overall symptom severity (OSS) score reflects individual chronic rhinosinusitis (CRS) symptoms and whether it can be measured using alternatives to the standard visual analog scale (VAS).

Methods: CRS patients from four sites across three continents rated their OSS scores, severities of nasal obstruction, nasal drainage, decreased sense of smell, facial pain/pressure and sleep disturbance using a standard VAS, VAS with labeled tick marks at every 1 centimeter, and by writing down their OSS on a scale of 0 - 100 (which was divided by 10), all of which lead to severity scores ranging from 0 - 10 in 0.1 intervals.

Short-term trivalent arsenic and hexavalent chromium exposures induce gut dysbiosis and transcriptional alteration in adipose tissue of mice.

Background: Inorganic arsenic [As(III)] and hexavalent chromium [Cr(VI)] can potentially affect metabolic functions. These heavy metal(s)/metalloids can also affect the gut microbial architecture which affects metabolic health. Here, we assessed the effects of short-term exposure of As(III) and Cr(VI) on key transcription factors in adipose tissues and on selected gut microbial abundances to understand the possible modulatory role of these toxicants on host metabolic health.

Pacemaker lead-related endocarditis with .

We report the first known case of -associated pacemaker lead endocarditis-a disease whose incidence and mortality are growing. A woman in her 70s with a history of transcatheter aortic valve replacement and pacemaker placement 7 months earlier presented with recurrent fevers. She visited the emergency department several times during the past 2 months for these fevers, and she had been given oral antibiotics for presumed urinary tract infections.