Publications by authors named "R S Ayyala"
: The design of alternative antipathogenic sprays has recently attracted much attention due to the limitations of existing formulations, such as toxicity and low and narrow efficacy. Polyethyleneimine (PEI) is a great antimicrobial polymer against a wide range of pathogens, but toxicity limits its use. Here, betainized PEI (B-PEI) was synthesized to decrease the toxicity of PEI and protonated with citric acid (CA), boric acid (BA), and HCl to improve antimicrobial activity.
View Article and Find Full Text PDFUtilization of magnetic resonance imaging (MRI) in the pediatric emergency room or urgent care setting for abdominopelvic indications has been increasing. The creation and implementation of rapid urgent MRI programs can have various challenges. The purpose of this article is to describe a framework for the creation of a rapid urgent abdominopelvic MRI program in the pediatric emergency room setting.
View Article and Find Full Text PDFArticle Synopsis
- Data-driven computational analysis in biomedical research is hindered by poor sharing of research outputs, affecting the transparency and reproducibility of studies.
- An analysis of 453 manuscripts from 2016-2021 found that over half did not share analytical code, with only 10% organizing their code in a reproducible format.
- To improve reproducibility and promote scientific collaboration, the study emphasizes the need for better awareness and practices around sharing code and data in the biomedical field.
Background: Ovarian enlargement is one of several findings of pathology, including ovarian torsion. With increasing use of MRI for acute abdominal pain in children, data for normal ovary size and appearance are needed.
Objective: To provide preliminary data on normal sizes of ovaries on MRI in pediatric patients.
Objective: To use time driven activity-based costing to characterize the provider cost of rapid MRI for appendicitis compared to other MRI examinations billed with the same Current Procedural Terminology codes commonly used for MRI appendicitis examinations.
Methods: Rapid MRI appendicitis examination was compared with MRI pelvis without intravenous contrast, MRI abdomen/pelvis without intravenous contrast, and MRI abdomen/pelvis with intravenous contrast. Process maps for each examination were created through direct shadowing of patient procedures (n = 20) and feedback from relevant health care professionals.