Latest Developments in Minimally Invasive Spinal Treatment in Slovakia and Its Comparison with an Open Approach for the Treatment of Lumbar Degenerative Diseases.

The study describes the benefits of MIS-TLIF (minimally invasive transforaminal lumbar interbody fusion) and compares them with OTLIF (open transforaminal lumbar interbody fusion). It compares blood loss, length of hospitalization stays (LOS), operation time, and return of the patient to the environment. A total of 250 adults (109 males and 141 females), mean age 59.

Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.

Zika virus (ZIKV) infection during infancy in a rhesus macaque (RM) model negatively impacts brain development resulting in long-term behavioral alterations. The current study investigated whether postexposure prophylaxis could alleviate these negative neurodevelopmental consequences. Three RM infants received a 14-day course of sofosbuvir (SOF; 15 mg/kg p.

Associations between prevalence of chronic diseases and socio-economic status in adult population of Slovakia.

Introduction: The study presents associations between prevalence of chronic diseases and selected socio-economic (SES) attributes in adult population of Slovakia and analyses the prevalence of chronic diseases in regions of Slovakia.

Methods: In total, 735 respondents (146 men and 589 women) with a mean age of 37.79 ± 13.

Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey.

With the ultimate goal of developing a more representative animal model of Alzheimer's disease (AD), two female amyloid-β-(Aβ) precursor protein-transgenic (APPtg) rhesus monkeys were generated by lentiviral transduction of the gene into rhesus oocytes, followed by fertilization and embryo transfer. The -transgene included the AD-associated Swedish K670N/M671L and Indiana V717F mutations () regulated by the human polyubiquitin-C promoter. Overexpression of was confirmed in lymphocytes and brain tissue.

World´s COVID-19 anti-pandemic measures in the context of postural and spine disorders in primary school children in Slovakia.

Introduction: This study was aimed to estimate the effect of one-year persistence of COVID-19 anti-pandemic measures on the posture and spine in children of younger school age in Slovakia.

Material And Methods: A total of 135 children aged between 6 and 9 years participated in this study. The examination of posture and spine was carried out in 4 schools in 4 different districts in Slovakia.