Publications by authors named "R Rujelman"

Background: Non-thyroidal illness (NTI) is frequent in hospitalized patients. Its recovery is characterized by a raise in TSH levels. However, the clinical significance of high TSH levels at admission in hospitalized elderly patients with NTI remains uncertain.

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Purpose: Overt hypothyroidism has adverse clinical consequences and might worsen prognosis in critically ill elderly patients. However, the difficult interpretation of thyroid function tests (TFT) due to non-thyroidal illness (NTI) has led to discouragement of screening for thyroid dysfunction. Our aim was to determine the prevalence of TFT compatible with hypothyroidism and to study its influence on mortality among hospitalized elderly patients.

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Article Synopsis
  • The study aimed to analyze the relationship between thyroid function tests (TFT) and morbidity/mortality rates in hospitalized older patients (over 60 years old) at Dr. Cesar Milstein Hospital from 2009 to 2010.
  • Out of 2,599 older patients, only 7% underwent TFTs; those tested were predominantly women in more serious conditions, with a majority showing non-thyroidal illness, while hypothyroid patients had worse clinical outcomes and higher morbidity/mortality rates.
  • The findings indicated that low total thyroxine (TT4) and high thyroid-stimulating hormone (TSH) levels were linked to poorer prognosis, suggesting that TFTs could be
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