Publications by authors named "R Ruiz de Gauna Lopez de Heredia"
We present the development of an experimental platform that can collect four frames of x-ray diffraction data along a single line of sight during laser-driven, dynamic-compression experiments at the National Ignition Facility. The platform is comprised of a diagnostic imager built around ultrafast sensors with a 2-ns integration time, a custom target assembly that serves also to shield the imager, and a 10-ns duration, quasi-monochromatic x-ray source produced by laser-generated plasma. We demonstrate the performance with diffraction data for Pb ramp compressed to 150 GPa and illuminated by a Ge x-ray source that produces ∼7 × 1011, 10.
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- Researchers aim to extend human healthspans by keeping cells functional and non-senescent, as aging appears to be genetically regulated in model organisms.
- A new human genetic disease linked to GIMAP5 deficiency leads to cell senescence, liver and immune dysfunction, and early death, highlighting GIMAP5's importance in longevity.
- GIMAP5 helps regulate the accumulation of harmful long-chain ceramides by interacting with a protein kinase (CK2), and targeting CK2 can restore function in GIMAP5-deficient cells, showing its role in maintaining immune health and longevity.
The 2021 Resolution on Oral Health by the 74th World Health Assembly supports an important health policy direction: inclusion of oral health in universal health coverage. Many healthcare systems worldwide have not yet addressed oral diseases effectively. The adoption of value-based healthcare (VBHC) reorients health services towards outcomes.
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