Aging and longevity: why knowing the difference is important to nutrition research.

Life expectancies after the age of 70 and the number of individuals living with age-related chronic conditions that affect daily activities continue to increase. Age-specific nutritional recommendations may help to decrease the incidence or severity of age-related debilitating chronic disorders. However, research in this area has seen limited success in identifying nutrition-related mechanisms that underlie the functional loss and chronic conditions that occur as a function of time.

Normal values of quantitative T2' in a spontaneously hypertensive stroke prone rat stem at 3T.

Introduction: Regarding therapy and prognosis of acute ischemic stroke the identification of ischemic penumbra is pivotal. A promising candidate is BOLD-imaging using qT2'-maps. For valid interpretation of experimental studies in animals normal values for qT2' are needed.

Changes in food intake and its relationship to weight loss during advanced age.

The results of extensive human and animal studies suggest that declining food intake and body weight observed in the later stages of life may be part of the normal progression of physiological decline observed during aging. Proposed etiologies cover a wide range of biological and psychological conditions. Studies in humans suggest an imbalance in homeostatic mechanisms governing hunger and satiety.

Use of antioxidant nutrients in the prevention and treatment of type 2 diabetes.

Type 2 diabetes, or non-insulin dependent diabetes mellitus (NIDDM), is increasingly common throughout the world. The World Health Organization has predicted that between 1997 and 2025, the number of diabetics will double from 143 million to about 300 million. The incidence of NIDDM is highest in economically developed nations, particularly the U.

Alterations in endogenous circadian rhythm of core temperature in senescent Fischer 344 rats.

We assessed whether alterations in endogenous circadian rhythm of core temperature (CRT) in aging rats are associated with chronological time or with a biological marker of senescence, i.e., spontaneous rapid body weight loss.