Publications by authors named "R Roshan"

Background: Ample evidence has been generated regarding the effectiveness of school-based mental health interventions as part of the continuum of care for children and capacity building of teachers to deal with the emotional and behavioral challenges of students. The increasing trend of utilization of teachers as the natural support system of children and the huge financial impact of public health interventions highlights the need to review all available evidence regarding multilevel factors that facilitate or pose a challenge to the provision of School Mental Health Programs (SMHP) using teachers as providers. The current review aims to map extracted evidence under the Consolidated Framework for Implementation Research (CFIR) domains to support future implementation research on school-based mental health services.

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Background And Rationale: Methicillin resistant Staphylococcus aureus (MRSA) colonization increases the risk of MRSA infection. Detecting MRSA colonization can influence postoperative outcomes and prolong hospital stay. The conventional standard culture method for detecting MRSA colonization has limitations in terms of sensitivity and turnaround time.

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Article Synopsis
  • The Cancer Immunotherapy Trials Network 12 study showed that pembrolizumab is safe and effective for treating advanced Kaposi sarcoma (KS) in people with HIV on antiretroviral therapy.
  • In a phase I trial involving 32 participants, 62.1% had a positive response to pembrolizumab, with even higher rates (87.5%) for those who hadn't received previous KS treatments.
  • The treatment led to significant progression-free survival, with a median of 28.2 months, and immune-mediated adverse events were effectively managed according to established guidelines.
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Article Synopsis
  • Tuberculosis (TB) is a major health issue in India, particularly osteoarticular TB, which can be difficult to diagnose but is treatable if caught early.
  • A study conducted at Nalanda Medical College followed 120 patients over 18 months, measuring various serum proteins before and during treatment.
  • Results indicated that disease progression caused changes in protein levels, but these changes could be reversed with the right medication, suggesting serum protein analysis could be a useful diagnostic tool for osteoarticular TB.
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