Microperimetry in hydroxychloroquine macular toxicity.

The aim was to evaluate the value of microperimetry (MP) in the early detection of toxic maculopathy caused by HCQ treatment in patients with normal fundoscopy, as well as normal structural optical coherence tomography (OCT). Microperimetry was performed in 13 patients under hydroxychloroquine treatment, who did not present fundoscopic or structural OCT alterations compatible with maculopathy. We used Nidek MP3s equipment (Nidek, Gamagori, Japan) with a 13-point pattern centered in fovea, in mesopic mode and in scotopic mode.

[Macular hole and Alport's syndrome].

Case Report: We present the clinical cases of two male patients of 38 and 39 years, diagnosed with Alport's syndrome, who suffered a bilateral macular hole and a giant unilateral macular hole with retinal thinning in the other eye, respectively.

Discussion: Alport's syndrome is a genetic disorder characterised by mutation of genes encoding type IV collagen, the main component of the internal limiting membrane, a structure identified in basal membrane of the retinal pigment epithelium-Brüch's membrane complex. This alteration can influence the predisposition to macular holes.

[Facial pain of cardiac origin].

Two cases of anginal pain limited to the mandible with secondary radiation of the pain to the neck and clavicular region are presented. Although the pain was initially diagnosed as odontogenic in origin, further historial workup suggest the suspicion of referred pain from coronary insufficiency. Appropriate medical referral confirmed diagnostic suspicions.