Publications by authors named "R Rodriguez-Alvarez"
Transplant Rev (Orlando)
December 2024
Article Synopsis
- * A working group has developed new consensus recommendations for CMV management in SOT recipients, integrating recent advancements in cell-mediated immunity monitoring.
- * These recommendations were rated for their evidence strength and quality using the GRADE system and were formally endorsed by a consensus meeting of experts.
Transplantation
July 2024
Article Synopsis
- A study analyzed the management and mortality outcomes of nontuberculous mycobacterial (NTM) infections in solid organ transplant (SOT) recipients, focusing on data from 2008 to 2018.
- Out of 85 patients with NTM infections and 169 matched controls, one-year mortality was significantly higher in the infected group (20%) compared to controls (3%), particularly among those who had lung transplants.
- Factors like time to treatment and changes in immunosuppression levels did not show a direct correlation with mortality rates among the patients.
Transplantation
November 2024
Article Synopsis
- Isavuconazole (ISA) and voriconazole (VORI) are both recommended first-line treatments for invasive aspergillosis, but there hasn't been a direct comparison in solid organ transplant recipients.
- A study analyzed data from two cohorts of patients treated with either ISA or VORI, focusing on clinical response, mortality rates, adverse events, and treatment discontinuation after 12 weeks.
- Results showed no significant difference in clinical outcomes between ISA and VORI, but ISA had fewer adverse events and lower rates of treatment discontinuation, indicating better tolerability.
