Socio-economic disparities in the utilization of improved sanitation facilities among Indian households.

Despite the significant improvement in sanitation coverage , utilization of improved sanitation still does not reach the optimal level across all socioeconomic groups in India. Therefore, achieving improved sanitation facilities and reducing all forms of inequality United Nations Sustainable Development Goal [SDG 6.2] by 2030 is a big challenge to the most populous country in the world.

MMIT-DDPM - Multilateral medical image translation with class and structure supervised diffusion-based model.

Unified translation of medical images from one-to-many distinct modalities is desirable in healthcare settings. A ubiquitous approach for bilateral medical scan translation is one-to-one mapping with GANs. However, its efficacy in encapsulating diversity in a pool of medical scans and performing one-to-many translation is questionable.

Patient-derived tumor organoid and fibroblast assembloid models for interrogation of the tumor microenvironment in esophageal adenocarcinoma.

The tumor microenvironment (TME) comprises all non-tumor elements of cancer and strongly influences disease progression and phenotype. To understand tumor biology and accurately test new therapeutic strategies, representative models should contain both tumor cells and normal cells of the TME. Here, we describe and characterize co-culture tumor-derived organoids and cancer-associated fibroblasts (CAFs), a major component of the TME, in matrix-embedded assembloid models of esophageal adenocarcinoma (EAC).

Elevating the energetic capabilities of metal coordination compounds by incorporating nitrate anions.

In the realm of energetic materials research, there has been notable interest in energetic coordination compounds (ECCs) owing to their remarkable thermal stability and resistance to mechanical stimuli. This study successfully demonstrated the synthesis of an azole-based C-C bonded ECC1 under ambient conditions. A comprehensive characterization study, employing techniques such as IR, TGA-DSC, NMR and single-crystal X-ray diffraction analysis, was conducted.

Distribution, toxicity load and risk assessment of heavy metals in the groundwater of Dhemaji, Assam, India.

Metal contamination in drinking water has drawn attention since it gravely jeopardizes human health. This study was conducted in pre- and post-monsoon season in 2021 at Dhemaji, Assam, India. It characterized metal pollutants in groundwater, their distribution, possible sources, and evaluated the potential toxicity and associated health risk assessment.