Publications by authors named "R Rantanen"
Background: Partial or complete thymectomy is routinely performed in paediatric open-heart surgeries when treating congenital heart defects. Whether or not thymectomised children require systematic immunological monitoring later in life is unknown. The objective of this study was to investigate the effects of preoperatively and postoperatively used antibiotics, hospitalisation and surgical complications on self-reported immunological vulnerability in paediatric patients with early thymectomy to better recognise the patients who could benefit from immunological follow-up in the future.
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- This study looked at how early thymectomy during heart surgery affects kids' health in Finland.
- It involved kids aged 1-15 who had heart surgery and compared their health to other kids without heart issues.
- The results showed that kids who had the surgery were more likely to get infections, pneumonia, asthma, and wheezing than those who didn’t have the surgery, pointing out the need for better health check-ups for these kids.
Apolipoprotein E (apoE) polymorphism is a genetic determinant of serum lipoprotein levels and coronary heart disease risk. ApoE appears in three major isoforms E2, E3 and E4, coded by corresponding alleles epsilon 2, epsilon 3 and epsilon 4. These give six different phenotypes.
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