3D printed needleless injector based on thermocavitation: analysis of impact and penetration depth in skin phantoms in a repetitive regime.

A global issue that requires attention is the duality between the shortage of needles for regular vaccination campaigns and the exponential increase in syringe and needle waste from such campaigns, which has been exacerbated by the COVID-19 pandemic. In response to this problem, this study presents a 3D printed needleless injector based on thermocavitation. The work focused on investigating the interaction of the resulting liquid jets with skin phantoms at different concentrations (1-2%), emphasizing their impact and penetration depth in a repetitive regime.

Evaluation of antifungal activity of visible light-activated doped TiO nanoparticles.

Titanium dioxide (TiO) is a well-known material for its biomedical applications, among which its implementation as a photosensitizer in photodynamic therapy has attracted considerable interest due to its photocatalytic properties, biocompatibility, high chemical stability, and low toxicity. However, the photoactivation of TiO requires ultraviolet light, which may lead to cell mutation and consequently cancer. To address these challenges, recent research has focused on the incorporation of metal dopants into the TiO lattice to shift the band gap to lower energies by introducing allowed energy states within the band gap, thus ensuring the harnessing of visible light.

Enhancing 3D human pose estimation with NIR single-pixel imaging and time-of-flight technology: a deep learning approach.

The extraction of 3D human pose and body shape details from a single monocular image is a significant challenge in computer vision. Traditional methods use RGB images, but these are constrained by varying lighting and occlusions. However, cutting-edge developments in imaging technologies have introduced new techniques such as single-pixel imaging (SPI) that can surmount these hurdles.

Bio-inspired apparatus to produce luminescent cavitation in a rigid walled chamber.

A mechanical device inspired by the rapid rotational motion of the pistol shrimp plunger has been developed to experimentally study the contraction/expansion dynamics of a gas bubble inside a confined liquid volume and in the vicinity of solid surfaces. The apparatus consists of a limb with a V-shaped end, which fits into a socket forming a cylindrical compression chamber. Air bubbles of different sizes and in different positions inside the chamber were seeded to study their shape evolution in liquids when subjected to pressure pulses induced by the limb closure.

Improved spatial speckle contrast model for tissue blood flow imaging: effects of spatial correlation among neighboring camera pixels.

Significance: Speckle contrast analysis is the basis of laser speckle imaging (LSI), a simple, inexpensive, noninvasive technique used in various fields of medicine and engineering. A common application of LSI is the measurement of tissue blood flow. Accurate measurement of speckle contrast is essential to correctly measure blood flow.