Publications by authors named "R Rameshkumar"
Objectives: This study aimed to explore the effect of antiseizure medications (ASM) on thyroid function in children with epilepsy.
Methods: A prospective study involving children between 6 months and 12 years of age with new-onset seizures who took ASM within 2 months was conducted in the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India, between August 2019 to March 2022. Thyroid function tests-free T3, free T4 and thyroid stimulating hormone (TSH)-were done at baseline and after completing 3 months by competitive immunoassay using direct chemiluminescent technology.
Objectives: To compare high-flow nasal cannula (HFNC) versus nasal prong bubble continuous positive airway pressure (b-CPAP) in children with moderate to severe acute bronchiolitis.
Design: A randomized controlled trial was carried out from August 2019 to February 2022. (Clinical Trials Registry of India number CTRI/2019/07/020402).
High-flow nasal oxygen in infants and children for early respiratory management of pneumonia-induced acute hypoxemic respiratory failure: the CENTURI randomized clinical trial.
Intensive Care Med Paediatr Neonatal
April 2024
Article Synopsis
- This study compared the effectiveness of high-flow nasal cannula (HFNC) oxygen therapy versus low-flow oxygen support (LFOS) in children under 5 with acute hypoxemic respiratory failure from severe pneumonia in low-middle-income countries.
- An open-label randomized trial involved 244 children, analyzing the failure rates of treatment within 72 hours, where HFNC displayed a significantly lower failure rate (7.3%) compared to LFOS (20%).
- The conclusion indicated that early use of HFNC resulted in better outcomes and fewer necessary intubations, highlighting its potential as a preferred treatment for young children with this condition.
Article Synopsis
- The study aimed to evaluate the impact of two fluid resuscitation methods—balanced crystalloid (MES) and 0.9% saline—on kidney function in children with septic shock.
- Conducted in pediatric intensive care units across India from 2017 to 2020, the trial involved 708 children under 15 who were randomly assigned to receive either MES or saline for the first week of treatment.
- Results showed that those receiving MES experienced a significantly lower rate of acute kidney injury compared to saline (21% vs. 33%), while there was no significant difference in ICU mortality between the two groups.
Introduction: The chest X-ray (CXR) is the standard of practice to assess the tip of the endotracheal tube (ETT) in ventilated children. In many hospitals, it takes hours to get a bedside CXR, and it has radiation exposure. The objective of this study was to find the utility of bedside ultrasound (USG), in assessing the ETT tip position in a Pediatric Intensive Care Unit (PICU).
View Article and Find Full Text PDF