Reliability and Validity of the Turkish Version of Early-Onset Scoliosis Self-Report Questionnaire.

Objective: Early-Onset Scoliosis Self-Report Questionnaire (EOSQ-SELF) is a recently developed self-reported questionnaire based on the widely adopted Early-Onset Scoliosis Questionnaire and evaluates health-related quality of life in children with early-onset scoliosis over 8 years of age. To date, the questionnaire does not have a validated version in Turkish. The aim of this study was to translate EOSQ-SELF into Turkish and evaluate its reliability and validity.

Shedding new light on quadrupolar 1,4-dihydropyrrolo[3,2-]pyrroles: impact of electron-deficient scaffolds over emission.

In this work, we disclose a series of seven quadrupolar centrosymmetric 1,4-dihydropyrrolo[3,2-]pyrroles (DHPPs) linked to the two peripheral, strongly electron-accepting heterocycles such as benzoxadiazole, benzothiadiazole and benzoselenadiazole. This represents the first study probing the influence of electron-deficient heterocycles, rather that small electron-withdrawing substituents, on photophysics of DHPPs. These new acceptor-donor-acceptor hybrid dyes exhibit an appreciable combination of photophysical properties including absorption maxima in the range of 470-620 nm, and emission in the range of 500-720 nm with fluorescence quantum yields reaching 0.

Nonradiative Deactivation of the Fluorescent Ag-DNA and Ag-DNA Emitters: The Role of Water.

The luminescent quantum yield of silver-cluster emitters stabilized by short oligonucleotides (Ag-DNA) may be efficiently tuned by replacing nucleobases in their stabilization DNA matrices with analogues. In the present study, we proposed a valuable and straightforward theoretical methodology for assessing the photophysical behaviors emerging in Ag-DNA emitters after excitation. Using green Ag-DNA and near-IR Ag-DNA emitters we demonstrate how point guanine/inosine replacement could affect the photophysical rate constants of radiative/nonradiative processes.

pH-dependent binding of ATP aptamer to the target and competition strands: Fluorescent melting curve fitting study.

The pH varies in different tissues and organelles and also changes during some diseases. In this regard, the application of molecular switches that use a competition-based aptamer switch design in biological systems requires studying the thermodynamics of such systems at different pH values. In this work, we studied the binding of the classical ATP aptamer to ATP and competition strands under different pH and ionic conditions using fluorescent melting curve analysis.

Neutral vs Charged Luminescent Radicals: Anti-Kasha Emission and the Impact of Molecular Surrounding.

Organic luminescent materials attract growing interest as an elegant solution for sustainable and inexpensive light-emitting devices. Most of them are neutral-emitting molecules with an implicit restriction of 25% internal quantum efficiency due to a spin-forbidden nature of the T → S transition. Utilizing organic radicals allows one to overcome such limits by theoretically boosting quantum yield up to 100%.