Publications by authors named "R Raffaele"

Road traffic accidents (RTAs) are a leading cause of morbidity and mortality worldwide, frequently resulting in traumatic brain injuries (TBIs), skull fractures, and spinal injuries. This manuscript examines the forensic aspects of head trauma caused by RTAs, focusing on the role of autopsy and imaging in diagnosing and characterizing injuries. Through a systematic review of the literature, the study highlights the mechanisms of injury, including high-speed collisions, whiplash, and pedestrian impacts, and explores their pathological consequences, such as subarachnoid hemorrhage, intracranial hemorrhage, and diffuse axonal injury.

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Background/objectives: Differential diagnosis of sudden cardiac death (SCD) remains challenging, particularly in cases lacking evident structural abnormalities. Cardiac markers have been proposed as useful tools for this differentiation in forensic contexts. However, key issues include the influence of postmortem interval (PMI) on marker stability and the limitations of traditional approaches that focus on pericardial fluid, which requires invasive sampling compared to peripheral blood.

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Background: Gender-based violence against women and its lethal outcome, femicide, represent important issues around the world. Although governments have passed specific laws, official data on gender-related violence and femicide are often absent and/or incomplete, difficult to access, rarely updated, contested and underestimated due to stigma, victim blaming or issues of legal interpretation. Femicide is an intentional killing in which a woman is murdered by an individual for misogyny and gender-related reasons.

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Article Synopsis
  • Toxic Epidermal Necrolysis (TEN) and Steven-Johnson Syndrome (SJS) are severe and potentially life-threatening skin reactions triggered by medications, making their treatment difficult.
  • This study examines two cases of children with TEN and SJS who were treated with a combination of antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT), in addition to regular supportive care.
  • The treatment led to notable improvement in the children's oral health within a few days, allowing them to begin eating again, suggesting that aPDT and PBMT might effectively support recovery from oral injuries caused by TEN and SJS.
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