Incorporation of metal-doped silicate microparticles into collagen scaffolds combines chemical and architectural cues for endochondral bone healing.

Regeneration of large bone defects remains a clinical challenge until today. While existing biomaterials are predominantly addressing bone healing via direct, intramembranous ossification (IO), bone tissue formation via a cartilage phase, so-called endochondral ossification (EO) has been shown to be a promising alternative strategy. However, pure biomaterial approaches for EO induction are sparse and the knowledge how material components can have bioactive contribution to the required cartilage formation is limited.

How Inclusive Are Patient Decision Aids for People with Limited Health Literacy? An Analysis of Understandability Criteria and the Communication about Options and Probabilities.

Objective: Patient decision aids (PtDAs) can support shared decision making. We aimed to explore how inclusive PtDAs are for people with limited health literacy (LHL) by analyzing 1) the understandability of PtDAs using established criteria, 2) how options and probabilities of outcomes are communicated, and 3) the extent to which risk communication (RC) guidelines are followed.

Methods: In a descriptive document analysis, we analyzed Dutch PtDAs available in 2021 that met the International Patient Decision Aid Standards.

Synthesis of Lewis acid-base adducts between potassium dihydrogenpnictogenides and group 13 Lewis acids.

Lewis acid-base adducts between potassium dihydrogenpnictogenides [K(18c6)PnH2] (Pn = P, As) and Trialkylgallanes (GaMe3, GaEt3, GatBu3) as well as BH3 were synthesized. In the course of these investigations, we were able to fully characterize a row of compounds of the type [K(18c6)(thf)0‑2][PnH2(ER3)2] (E = B: R = H; E = Ga: R = Me, Et, tBu). Based on the successful syntheses of these species, we also synthesized several compounds of the composition [K(18c6)(thf)0‑2][Pn(SiMe3)2(ER3)n] (n = 1, 2) starting from [KPn(SiMe3)2] (Pn = P and As) and ER3 (E = B, Al, In: R = Me; E = Ga: R= Me, Et, tBu).

Effects of land cover and protected areas on flying insect diversity.

Widespread insect losses are a critical global problem. Mitigating this problem requires identifying the principal drivers across different taxa and determining which insects are covered by protected areas. However, doing so is hindered by missing information on most species owing to extremely high insect diversity and difficulties in morphological identification.

Minimally invasive balloon-reduction of acute Hill-Sachs-lesions and impression fractures after shoulder dislocation - an experimental approach.

Background: The shoulder is the joint most often affected by dislocations. It is known that bony defects of the glenoid and/or humerus can lead to recurrent dislocations even after arthroscopic shoulder stabilization. To prevent recurrent instability, it appears reasonable to reduce fresh and larger Hill-Sachs lesions (off-track lesions).