Am J Respir Crit Care Med
March 2025
Rationale: group bacteria (MABS) cause lethal infections in people with chronic lung diseases. Transmission mechanisms remain poorly understood; the detection of dominant circulating clones (DCCs) has suggested potential for person-to-person transmission.
Objectives: This study aimed to determine the role of drinking water in the transmission of MABS.
Background: Recent advancements in brachytherapy necessitate precise dose calculations, transitioning from the traditional TG43 planning methods to the more sophisticated TG186 recommendations. However, the availability of accessible and efficient Monte Carlo (MC) codes capable of interfacing with clinical data for these advanced calculations remains limited.
Purpose: This study presents and validates eb_gui, a graphical user interface designed to seamlessly integrate DICOM clinical data with egs_brachy, a fast MC dose calculation algorithm tailored for brachytherapy applications.
Background: Low-energy x-ray beams used in electronic brachytherapy (eBT) present significant dosimetric challenges due to their high depth-dose gradients, the dependence of detector response on materials, and the lack of standardized dose-to-water references. These challenges have driven the need for Monte Carlo (MC) simulations to ensure accurate dosimetry. However, discrepancies in the physics models used by different MC systems have raised concerns about their dosimetric consistency, particularly in modeling bremsstrahlung interactions.
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