Publications by authors named "R R Kazwala"
Article Synopsis
- The study investigated risk factors for spotted fever group rickettsioses (SFGR) in the Kilimanjaro Region, Tanzania, focusing on febrile patients from local hospitals between 2012 and 2014.
- Of 1,190 participants, 54.6% had SFGR exposure, with 9.2% displaying acute SFGR; factors such as age, rural living, and temperature were significant in determining risk.
- The findings highlight that children under 2 years, rural residents, and those in cooler areas may be at higher risk for SFGR, suggesting a need for targeted prevention strategies and additional research on tick exposure.
Background: Brucellosis remains a significant health and economic challenge for livestock and humans globally. Despite its public health implications, the factors driving the endemic persistence of at the human-livestock interface in Tanzania remain poorly elucidated. This study aimed to identify the seroprevalence of infection in livestock and humans within a ranching system and determine associated risk factors for disease endemicity.
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- Campylobacteriosis and antimicrobial resistance (AMR) are major global concerns, especially in Africa, which has the highest campylobacteriosis rates and significant AMR prevalence in Campylobacter spp. from humans and animals.
- A study analyzed 178 Campylobacter isolates (81 from human diarrheal patients in Kenya and 97 from poultry in Tanzania) between 2006-2017, using whole-genome sequencing and antimicrobial susceptibility testing.
- The findings revealed high sequence type diversity and noted that multidrug resistance was significantly higher in poultry (40.9%) compared to humans (2.5%), highlighting the need for better antimicrobial management in livestock.
Article Synopsis
- The study focused on the prevalence of Q fever and rickettsioses in a pastoralist community in northern Tanzania, highlighting their commonality as causes of febrile illness.
- Analysis involved 228 febrile patients, where significant serological evidence indicated high exposure rates to C. burnetii and SFG Rickettsia, with a notable prevalence of probable cases.
- The research identified livestock slaughter as a significant risk factor, increasing the likelihood of acute Q fever and SFG rickettsioses among participants.
causes infections in humans and livestock. Bacterial isolates are challenging to obtain, and very little is known about the genomic epidemiology of this species in Africa. Here, we report the complete genome sequence of a isolate cultured from a febrile human in northern Tanzania.
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