Publications by authors named "R R Karthik"

Article Synopsis
  • The study reveals that microplastics in the Eastern Arabian Sea are mainly sourced from land-based activities, highlighting the relevance of global marine plastic pollution.
  • Quantification of microplastic concentrations and the use of hydrodynamic models aid in tracking their movement in coastal areas, providing valuable data for environmental analysis.
  • An Environmental Decision Support System (EDSS) was developed to guide policy decisions and integrated coastal zone management, aligning with international sustainability goals and emphasizing the need for effective waste management strategies.
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In the present study, we determine the synergistic activity of ertapenem with cefazolin and flucloxacillin against type A beta-lactamase producing Methicillin susceptible Staphylococcus aureus isolate. In the time kill assay, at standard inoculum, ertapenem with cefazolin showed >1 log kill and ertapenem with flucloxacillin demonstrated >2 log kill. When tested at high inoculum, both combinations achieved >1 log kill at 1x MIC.

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Article Synopsis
  • A study examined microplastics (MPs) in surface waters of the north-east coast of India, finding they were present in all samples with higher levels during the monsoon season.
  • The predominant types of MPs were fragments and fibers, and the study noted a significant variance in MP abundance related to land-based waste from the Hooghly River.
  • The research also identified various polymer types, highlighted polyethylene as the most common, and indicated a low-risk state for MP pollution, while emphasizing its implications for developing effective pollution reduction policies.
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Introduction: International guidelines recommend definitive combination antibiotic therapy for the management of serious infections involving carbapenem-resistant Acinetobacter (CRAB) species. The commonly available combination options include high-dose sulbactam, polymyxins, tetracyclines, and cefiderocol. Scanty prospective data exist to support this approach.

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Bacille Calmette-Guérin (BCG) vaccine has been used increasingly in immunotherapy, including treatment of non-muscle-invasive bladder cancer, as an adjuvant therapy in metastatic prostate cancer and metastatic melanoma. However, systemic infection from inadvertent intravenous (instead of intravesical) injection is uncommon and can have systemic ramifications. We encountered 3 patients with disseminated Mycobacterium bovis infection that ensued after intravenous BCG injection.

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