[Phosphodesterase type 5 inhibitors clinical efficiency and role in therapy for erectile dysfunction].

This article discusses the physiological mechanisms of erection and the pathophysiological basis of erectile dysfunction. Parameters characterizing the features of the pharmacokinetics and pharmacodynamics of drugs from the group of phosphodiesterase type 5 inhibitors (PDE-5i) are presented. The clinical efficacy and possible adverse effects of the most significant PDE-5i are considered.

[The development of immune-enzyme test-systems to diagnose rubella].

Two new immune-enzyme test-systems are developed to diagnose rubella using the natural antigen of rubella virus. The test-systems by their characteristics are equal with the known international models and can be recommended for large implementation in clinical diagnostic laboratories of health institutions to detect antibodies classes G, M to rubella virus both for disease diagnosis and mass serologic examination of immune status of population and evaluation of effectiveness of vaccination.

[The use of a magnetically abrasive finishing for sharpening the blades of medical instruments].

The method of magnetically abrasive working was first tried in medical industry as a finishing operation for the sharpening and removing of burrs from half-finished blades manufactured by means of vibration forging. The use of the sets for MAO-M-473 and EU-5 makes it possible to manufacture blades with the cutting edge less than or equal to 3 microns in width. The use of magnetically abrasive sharpening enables one to eliminate electrochemical polishing; excludes the appearance of superficial defects on the worked surface; raises corrosion stability and cyclic longevity of the articles.