Publications by authors named "R R Badertscher"
Identification of food intake biomarkers (FIBs) for fermented foods could help improve their dietary assessment and clarify their associations with cardiometabolic health. We aimed to identify novel FIBs for fermented foods in the plasma and urine metabolomes of 246 free-living Dutch adults using nontargeted LC-MS and GC-MS. Furthermore, associations between identified metabolites and several cardiometabolic risk factors were explored.
View Article and Find Full Text PDFThe identification of molecular biomarkers that can be used to quantitatively link dietary intake to phenotypic traits in humans is a key theme in modern nutritional research. Although dairy products (with and without fermentation) represent a major food group, the identification of markers of their intake lags behind that of other food groups. Here, we report the results from an analysis of the metabolites in postprandial serum and urine samples from a randomized crossover study with 14 healthy men who ingested acidified milk, yogurt, and a non-dairy meal.
View Article and Find Full Text PDFArticle Synopsis
- The decline in liquid milk consumption in Western countries is being offset by a rise in processed dairy products and plant-based milk alternatives, which are frequently marketed as substitutes for cow's milk.
- A study compared the nutritional content of 27 plant-based drinks to cow's milk, analyzing factors like protein, fat, vitamins, and minerals, as well as harmful residues such as glyphosate and arsenic.
- The findings indicated that while soy drinks contained more protein and certain vitamins than milk, most plant-based alternatives were low in protein and did not match the nutrient profile and quality of cow's milk, highlighting the need for better fortification in these products.
A simple, rapid, sensitive and robust gas chromatographic method was developed for the simultaneous determination of free volatile carboxylic acids (FVCA) in cheese and bacterial cultures. The target analytes were extracted and converted directly from the aqueous phase to their ethyl esters using headspace. The lower detection limits for the volatile carboxylic acids in the cheese samples were less than 0.
View Article and Find Full Text PDFBackground: Whereas the dietary intake of industrial trans fatty acids (iTFA) has been specifically associated with inflammation, cardiovascular disease, and type 2 diabetes, understanding the impact of dietary fats on human health remains challenging owing to their complex composition and individual effects of their lipid components on metabolism. The aim of this study is to profile the composition of blood, measured by the fatty acid (FAs) profile and untargeted metabolome of serum and the transcriptome of blood cells, in order to identify molecular signatures that discriminate dietary fat intakes.
Methods: In a parallel study, the molecular effects of consuming dairy fat containing ruminant TFA (rTFA) or margarine containing iTFA were investigated.