Publications by authors named "R R Al-Rashidi"

Autophagy, as a highly conserved cellular process, participates in cellular homeostasis by degradation and recycling of damaged organelles and proteins. Besides, autophagy has been evidenced to play a dual role through cancer initiation and progression. In the early stage, it may have a tumor-suppressive function through inducing apoptosis and removing damaged cells and organelles.

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Background: Patients with diabetes are at risk for developing diabetic foot ulcers (DFUs). It is recognized that type 2 diabetes (T2D) is distinguished by the loss of vitally important micronutrients because of the metabolic nature of this disease and its associated complexities.

Objective: This study was performed to determine the level of micronutrients in patients with DFUs in Saudi Arabia.

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Melasma, a commonly acquired hyperpigmentation skin condition, is usually treated with topical agents as the first line of management. This systematic review and meta-analysis aimed to assess the efficacy and safety of azelaic acid versus hydroquinone in treating melasma patients. We conducted a comprehensive search across four online databases (PubMed, Scopus, Web of Science, and Cochrane Library) from the time of their creation until May 28, 2023.

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Prostate carcinoma is a malignant situation that arises from genomic alterations in the prostate, leading to changes in tumorigenesis. The NF-κB pathway modulates various biological mechanisms, including inflammation and immune responses. Dysregulation of NF-κB promotes carcinogenesis, including increased proliferation, invasion, and therapy resistance.

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Article Synopsis
  • Splenic tumors are rare and can be malignant or benign; benign tumors like splenic hamartomas are particularly uncommon, with fewer than 160 cases reported, predominantly in adults.
  • A case study of a 14-year-old with abdominal pain led to the discovery of a splenic hamartoma through imaging, which was confirmed by pathology after spleen removal.
  • Splenic hamartomas are benign and often asymptomatic, requiring precise imaging and histology for diagnosis; they should be considered in the diagnosis of splenic masses.
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