Publications by authors named "R Prentice"

Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes with the total energy expenditure (TEE). In this study, we used the International Atomic Energy Agency Doubly Labeled Water Database to derive a predictive equation for TEE using 6,497 measures of TEE in individuals aged 4 to 96 years.

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This study explored the use of transperineal intestinal ultrasound (TPIUS) for assessment of ulcerative colitis (UC) in pregnancy. 8 pregnant women with UC underwent TP-US, clinical assessment and fecal calprotectin. TP-IUS was well tolerated and feasible with adequate rectal views obtained in all trimesters of pregnancy.

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Article Synopsis
  • - The study focused on evaluating the complications and usage of peripheral parenteral nutrition (PPN) in adult patients over a five-year period, highlighting its role as a short-term nutrition support alternative to centrally administered PN.
  • - Out of 381 patients analyzed, the most common reasons for PPN were ileus and gastrointestinal obstruction, with patients receiving about 65% of their energy and 58% of protein needs; malnutrition was identified in nearly half of the cohort.
  • - The overall complication rate for PPN was low at 8.7%, primarily involving cannula infiltration, and the study concluded that managed PPN can effectively address short-term nutritional needs while reducing the need for central line insertions.
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Article Synopsis
  • Doubly labeled water is the most reliable method for measuring total energy expenditure (TEE), but its accuracy can be affected by the isotope dilution space ratio (DSR).
  • This study explored factors like age, sex, ethnicity, body composition, and geographical elevation to see how they influence DSR, using various statistical analysis methods.
  • Results showed that while DSR decreased with age in individuals 60 and older, no significant effects were found from other variables, suggesting that previous estimates of TEE might be overestimating values for older individuals, especially those around 90 years old.
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Metabolomics has been used extensively to capture the exposome. We investigated whether prospectively measured metabolites provided predictive power beyond well-established risk factors among 758 women with adjudicated cancers [ = 577 breast (BC) and = 181 colorectal (CRC)] and = 758 controls with available specimens (collected mean 7.2 years prior to diagnosis) in the Women's Health Initiative Bone Mineral Density subcohort.

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