Restriction fragment length polymorphism study of Mycobacterium tuberculosis in Thailand using IS6110 as probe.

Setting: Three referral hospitals in central Thailand.

Objective: To determine the population structure of Mycobacterium tuberculosis isolated from the referral hospitals.

Design: Study of 211 isolates of the bacteria received from the hospitals in central Thailand by Southern hybridization, with IS6110 probe and other probes when indicated.

Histochemical stainings, biological cultures and therapeutic responses of granulomatous lymphadenitis in Ramathibodi Hospital-prospective study of 57 cases.

The study was designed to delineate the etiology of granulomatous lymphadenitis which is one of the most common lesions encountered in our routine surgical pathology practice. Fifty-seven lymph nodes diagnosed histopathologically as granulomatous lymphadenitis were cultured and stained by special histochemical stains for tuberculosis, fungus, anaerobic and aerobic bacteria. M.

Human pythiosis associated with thalassemia hemoglobinopathy syndrome.

Pythium infection (pythiosis) in humans has not previously been described, even in areas endemic for animal pythiosis. We report five patients with a unique presentation of fungal arteritis. The medium- to large-sized arteries were involved, and in some cases this involvement led to gangrene of the limbs, aneurysm formation, and ultimately fatal arterial leakage.

Spontaneous Vibrio vulnificus peritonitis and primary sepsis in two patients with alcoholic cirrhosis.

Two patients with alcoholic cirrhosis were seen on two separate occasions for fever, swollen legs, petechial hemorrhage, purpura, and cutaneous bullae. One patient ate oysters 2 days before the onset of illness. Vibrio vulnificus, a lactose-positive halophilic vibrio, was isolated from the ascitic and cutaneous fluid in both cases, and from the blood in one of the two cases.