Publications by authors named "R Podschun"
The cationic proinflammatory cytokine Interleukin 26 (IL-26) shows antibacterial activity and inhibits the replication of cytomegalovirus and hepatitis C virus. This study evaluates the early microbicidal activities of IL-26 against major bacterial species including multi-resistant variants and . Recombinant IL-26 was bacterially expressed and studied for its microbicidal effects in culture.
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- Bacteria and viruses were studied in both symptomatic pig farmers and their pigs in Schleswig-Holstein, Germany, with a total of 86 human and 495 pig swabs collected.
- Findings showed that Staphylococcus aureus was prevalent in both humans (62.8%) and pigs (36%), alongside frequent detection of human viruses like HRV and HCoV in farmers, and bacteria such as Haemophilus parasuis in pigs.
- A concerning 33.3% of human samples showed methicillin-resistant S. aureus (MRSA), indicating potential occupational transmission from pigs to farmers, while no cross-species virus transmission was found.
Antimicrobial peptides (AMPs) play an important role in the host defense against various microbes. One of the most efficient human AMPs is the human beta defensin-3 (hBD-3) which is produced by, e.g.
View Article and Find Full Text PDFBackground: Multidrug-resistant bacteria represent a substantial global burden for human health, potentially fuelled by migration waves: in 2015, 476,649 refugees applied for asylum in Germany mostly as a result of the Syrian crisis. In Arabic countries, multiresistant bacteria cause significant problems for healthcare systems. Currently, no data exist describing antibiotic resistances in healthy refugees.
View Article and Find Full Text PDFAim: The aim of the present study was to demonstrate the possible relation between periodontal health status and infections associated with osteosynthesis materials (OMs) used in the oral and maxillofacial reconstruction.
Material And Methods: The study group consisted of 32 individuals which were subdivided into two groups regarding their PSI scores. After the removal of the osteosynthesis plates, microbial colonization was assessed via microbiological cultivation, fluorescence microscopy and scanning electron microscopy.