Publications by authors named "R Pisapia"
Article Synopsis
- COVID-19 has been linked to increased cases of pneumothorax (PTX) and pneumomediastinum (PNM), leading to concerns about poor patient outcomes and factors affecting mortality.
- This observational study, analyzing data from nearly 12,000 COVID-19 patients in central Italy, identified specific risk factors for 28-day mortality and need for intubation related to pulmonary barotrauma.
- Key risk factors for higher mortality included elevated SOFA scores, use of vasopressors, hypercapnia, low PaO/FiO ratio, and existing cardiovascular disease, while variants of concern did not impact mortality rates.
Objectives: The aim of the study was to describe a cohort of B-cell-depleted immunocompromised (IC) patients with prolonged or relapsing COVID-19 treated with monotherapy or combination therapy.
Methods: This is a multicenter observational retrospective study conducted on IC patients consecutively hospitalized with a prolonged or relapsing SARS-CoV-2 infection from November 2020 to January 2023. IC COVID-19 subjects were stratified according to the monotherapy or combination anti-SARS-CoV-2 therapy received.