Interdisciplinary and minimally invasive approach to restoring aesthetics and periodontal health using a digital workflow.

Dental veneers are a popular option for enhancing smile aesthetics. While both ceramic and composite veneers are effective, achieving optimal outcomes often requires meticulous planning and interdisciplinary collaboration. A woman in her early 30s presented with dissatisfaction due to poorly executed direct composite veneers from teeth #15 to #25, which led to biofilm accumulation and gingival inflammation.

A project to define standards for radiology staffing, education and training across the European Union.

The European Union Radiation, Education, Staffing & Training (EU-REST) study was a European Commission-funded, 24-month project that analysed workforce availability, education and training needs to ensure quality and safety aspects of medical applications involving ionising radiation in the EU and developed staffing and education/training guidelines for key professional groups involved in ensuring radiation safety and quality of medical radiation applications in the EU Member States. This article outlines the origin, development, goals and overall structure of the project. CRITICAL RELEVANCE STATEMENT: This article provides a concise overview of the EU-REST project, which analysed the workforce availability of health professionals involved in the use of ionising radiation for diagnostic and therapeutic procedures and the corresponding education and training in radiation protection.

Towards Validation of Clinical Measures to Discriminate Between Nociceptive, Neuropathic and Nociplastic Pain: Cluster Analysis of a Cohort with Chronic Musculoskeletal Pain.

Objectives: The International Association for the Study of Pain defines three pain types presumed to involve different mechanisms - nociceptive, neuropathic and nociplastic. Based on the hypothesis that pain types should guide matching of patients with treatments, work has been undertaken to identify features to discriminate between them for clinical use. This study aimed to evaluate the validity of features to discriminate between pain types.

Bacteria-derived 3-hydroxydodecanoic acid induces a potent anti-tumor immune response via the GPR84 receptor.

Despite advances in cancer treatment, the development of effective therapies remains an urgent unmet need. Here, we investigate the potential of bacteria-derived metabolites as a therapeutic alternative for the treatment of cancer. We detect 3-hydroxydodecanedioic acid in the serum of tumor-bearing mice treated with serum from mice previously supplemented with a mix of Clostridiales bacteria.