Publications by authors named "R Perez Calderon"

Background: Previous research on the interaction of physical activity and sleep on depressive symptoms was mostly cross-sectional or conducted with children or young adults. This study examines the main and interactive associations of physical activity and sleep duration with depressive symptoms over a 3-year period among middle-aged and older Chinese adults.

Methods: Data from 4269 Chinese adults aged 45 or older from the China Health and Retirement Longitudinal Study (CHARLS) were used.

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Failure to rapidly diagnose tuberculosis disease (TB) and initiate treatment is a driving factor of TB as a leading cause of death in children. Current TB diagnostic assays have poor performance in children, and identifying novel non-sputum-based TB biomarkers to improve pediatric TB diagnosis is a global priority. We sought to develop a plasma biosignature for TB by probing the plasma proteome of 511 children stratified by TB diagnostic classification and HIV status from sites in four low- and middle-income countries, using high-throughput data-independent acquisition mass-spectrometry (DIA-PASEF-MS).

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Greenhouse vegetable production is often associated with the excessive use of nitrogen fertilizers and a high rate of nitrate accumulation. We evaluated the uptake, translocation, and accumulation of nitrate in chard and spinach under greenhouse conditions with optimal fertilization. The results revealed low levels of nitrate in the leachates and substrates (chard ˃ spinach).

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Article Synopsis
  • This study investigates the link between EEG-measured sleep patterns and depressive symptoms in older adults living in the community.
  • Researchers analyzed data from 66 older adults with sleep complaints, measuring their sleep using a sleep EEG device and depressive symptoms with the Geriatric Depression Scale.
  • The findings indicate that lighter sleep (stages N1 and N2), reduced deep sleep (N3), and more frequent awakenings are associated with increased depressive symptoms, suggesting that improving sleep quality could help reduce depression in this population.
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Infectious disease is the result of interactions between host and pathogen and can depend on genetic variations in both. We conduct a genome-to-genome study of paired human and Mycobacterium tuberculosis genomes from a cohort of 1556 tuberculosis patients in Lima, Peru. We identify an association between a human intronic variant (rs3130660, OR = 10.

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