Publications by authors named "R Peel"
Background: The effectiveness of the NSW Health "Get Healthy Information and Coaching Service(Get Healthy) to facilitate weight loss on a population scale has been documented, but this was based on self-reported measures. Our study aims to test the effectiveness of the Get Healthy Service on objectively measured weight, BMI, waist circumference, and changes in other health behaviours, including nutrition, physical activity and alcohol intake.
Methods: Men and women aged 40-70 years (n = 154) with pre-diabetes (5.
Background: Providing recommended amounts of rehabilitation for stroke and neurological patients is challenging. Telerehabilitation is viable for delivering rehabilitation and an acceptable adjunct to in-person therapy. NeuroRehabilitation OnLine (NROL) was developed as a pilot and subsequently operationalised as a regional innovation embedded across four National Health Service (NHS) Trusts.
View Article and Find Full Text PDFBackground: Hypertension is a key risk factor for major adverse cardiovascular events but remains difficult to treat in many individuals. Dietary interventions are an effective approach to lower blood pressure (BP) but are not equally effective across all individuals. BP is heritable, and genetics may be a useful tool to overcome treatment response heterogeneity.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates whether the pneumococcal polysaccharide vaccine (PPV) can reduce atherosclerosis in humans, similar to findings in mouse models through molecular mimicry.
- A national trial, AUSPICE, is underway to track cardiovascular disease (CVD) events and includes a substudy measuring various biomarkers over four years.
- Results show increased anti-pneumococcal antibodies in the vaccinated group, but no improvement in CVD surrogate markers or metabolic indicators, with final findings on actual CVD events pending next year.
Background: no studies have compared the predictive validity of different dementia risk prediction models in Australia.
Objectives: (i) to investigate the predictive validity of the Australian National University-Alzheimer's Disease Risk Index (ANU-ADRI), LIfestyle for BRAin Health (LIBRA) Index and cardiovascular risk factors, ageing and dementia study (CAIDE) models for predicting probable dementia/cognitive impairment in an Australian cohort. (ii) To develop and assess the predictive validity of a new hybrid model combining variables from the three models.