The variable surface glycoproteins of Trypanosoma equiperdum are phosphorylated.

The phosphoproteins from three Trypanosoma equiperdum variants were studied by labelling the parasites in vivo with 32P. Phosphoprotein analysis reveals the presence of a 58 000 mol. wt.

Macrophage function during Trypanosoma musculi infection in mice.

Quantitative and functional changes in peritoneal macrophages from mice infected with Trypanosoma musculi were investigated. Increase in the number and size and in the protein content of peritoneal macrophages and the presence of parasites in the peritoneal activity were observed during the course of parasitemia. Induced releases of H2O2 by macrophages were increased during parasitemia, but H2O2 release returned to normal after infection.

Immune depression and macroglobulinemia in experimental subchronic trypanosomiasis.

The effects of subchronic trypanosomiasis upon immune responses were examined in Trypanosoma gambiense infection and in subcurative treatment of T. brucei- and T- equiperdum-infected mice. About 60% of the mice infected with T.

Anti-immunoglobulins and heterophil agglutinins in experimental trypanosomiasis.

Rheumatoid factor (RF)-like substances and heterophil agglutinins (HA) were induced in rabbits by infection with a strain of Trypanosoma equiperdum. Infection with a T. gambiense strain produced HA, but no RF.