Background: Allium ramosum is an important member of the genus Allium, which is commonly known as Chinese chive or fragrant-flowered garlic. Conserving the genetic diversity of different species of Allium is crucial, and cryopreservation has emerged as an important strategy for long-term conservation of alliums.
Objective: To develop a reliable protocol for the cryoconservation of A.
Annulated C-glycosides are widely recognized for their natural abundance and diverse bioactivity. Traditional synthesis emphasizes stereoselective α/β C-glycoside formation, but efficiently engaging both reactive carbons of glycosyl donors remains challenging. This study introduces a novel domino sequence using substituted glycals and β-naphthols under Lewis acid catalysis, generating glycosylated intermediates that undergo cascade reactions to yield annulated 1,2-C-glycosides.
View Article and Find Full Text PDFBackground: COVID-19 pandemic had unprecedented global impact on health and society, highlighting the need for a detailed understanding of SARS-CoV-2 evolution in response to host and environmental factors. This study investigates the evolution of SARS-CoV-2 via mutation dynamics, focusing on distinct age cohorts, geographical location, and vaccination status within the Indian population, one of the nations most affected by COVID-19.
Methodology: Comprehensive dataset, across diverse time points during the Alpha, Delta, and Omicron variant waves, captured essential phases of the pandemic's footprint in India.
Microplastic particles have become ubiquitous in various ecosystems due to a drastic increase in plastic use and its consequent litter. The biological effects of these plastic particles on aquatic fauna are well-documented. However, the study of their accumulation and subsequent impact on terrestrial flora and fauna is in its initial stages.
View Article and Find Full Text PDFThe gut microbiome plays a pivotal role in human health, influencing digestion, immunity, and disease prevention. Beneficial gut bacteria such as , , and contribute to metabolic regulation and immune support through bioactive metabolites like short-chain fatty acids (SCFAs). Dietary patterns rich in prebiotics, fermented foods, and plant-based bioactive compounds, including polyphenols and flavonoids, promote microbiome diversity and stability.
View Article and Find Full Text PDF