Publications by authors named "R P Vergouwen"

The effects of prenatal X irradiation on postnatal development of the CBA/P mouse testis was studied. At days 14, 15 and 18 post coitus pregnant female mice were exposed to single doses of X rays ranging from 0.25-1.

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The effects of total-body X irradiation on the prepubertal testis of the CBA/P mouse have been studied. At either day 14 or day 29 post partum male mice were exposed to single doses of X rays ranging from 1.5-6.

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The postnatal development of body and testis weight and the size of the testicular cell populations were studied in CBA mice up to day 52 post partum. The body weight increased from 1.3 g at day 1 to 22.

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Assuming that spermatogonial multiplication in primates will not be fundamentally different from that in non-primates it can be deduced that Ap and Ad spermatogonia in primates are analogous to the undifferentiated spermatogonia in non-primates. Ap and Ad spermatogonia consist of single, pairs and chains of cells, among which the single cells likely are the stem cells. The single Ap are the active stem cells while the single Ad only become active after cell loss.

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