Hypercapnia leading initially to activation of synaptic activity and of pace-maker mechanism is accompanied later by inactivation of the electro-excitable membrane and is completed by loss of chemosensitivity. Restoration of the properties of the neurone following transition to normal atmospheric air develops in reverse order. All hypercapnic changes of the properties of the electroexcitable and chemosensitive membrane take place at a constant level of the membrane potential which points to stability of K-Na-pump.
View Article and Find Full Text PDFZh Vyssh Nerv Deiat Im I P Pavlova
May 1975