Publications by authors named "R P Sanjay"
Being the second most prevalent metal oxide, zinc oxide (ZnO) nanomaterials have been widely studied and found to exhibit promising applications in various domains of biomedicine and agriculture. Considering the enhanced bioactivities displayed by secondary metabolite (SM) derived ZnO nanomaterials, present study was undertaken to evaluate the efficacy of ZnO nanoflake (NF) derived from Zerumbone (Zer), a sesquiterpenoid from Zingiber zerumbet rhizome with diverse pharmacological properties. ZnO NF prepared by homogeneous precipitation method using ZnSO.
View Article and Find Full Text PDFArticle Synopsis
- Hand, foot, and mouth disease (HFMD) is a childhood infection primarily caused by enteroviruses, characterized by fever and a rash on hands, feet, and mouth, with changing virus types observed in South India from 2015 to 2017.
- In a study analyzing samples from suspected HFMD cases, CVA6 was identified as the most common virus (64% of cases), followed by CVA16 and CVA10, while 20% of cases could not be typed.
- The majority of affected individuals were children under five years old, indicating a strong prevalence in young children during this period.
Background: This study was carried out to understand the circulating genotypes of Hepatitis A virus (HAV) in South West, East and North East India during the period 2017-2018 as a part of acute febrile illness surveillance at the Manipal Institute of Virology.
Methods: Archived serum samples of 48 Hepatitis A confirmed cases were subjected to RNA extraction using QIAamp® Viral RNA Mini Kit (QIAGEN, Germany). The samples with molecular confirmation for HAV by reverse transcriptase real-Time PCR (Real Star® HAV RT-PCR Kit 2.
Article Synopsis
- EV-D68 is a new enterovirus linked to serious respiratory issues and paralysis, with few cases reported globally, including one in India.
- The study analyzed throat swab samples from patients in South India to identify and classify enteroviruses, discovering three cases of EV-D68 in young children with pneumonia but no neurological problems.
- The findings show that the EV-D68 strains belong to a new subclade (B3) and highlight the need for better surveillance of this virus in India.
Tumor lysis syndrome (TLS) is the phenomenon of metabolic derangements that typically follows the initiation of cytotoxic chemotherapy. Metabolic disturbances include hyperphosphatemia, hyperkalemia, hyperuricemia and hypocalcemia. Hematological malignancies are associated with spontaneous TLS (STLS), which is cell lysis in the absence of chemotherapy.
View Article and Find Full Text PDF