Publications by authors named "R P Roine"
Background: Behavioral therapy has proved effective as rumination therapy. Our objective was to treat rumination patients using multidisciplinary behavioral therapy aimed at reducing ≥2 of the rumination score.
Methods: All patients fulfilled Rome IV criteria for rumination and were referred to speech therapy for psychoeducation, diaphragmatic breathing exercises and guided eating, physiotherapy for exercises to relax the thoracic and abdominal muscles, and consultation with the psychologist and the dietitian.
Article Synopsis
- Inhaled xenon combined with hypothermia was tested on comatose patients who survived out-of-hospital cardiac arrest (OHCA) to see if it could protect gray matter in the brain.
- A study of 110 patients found that those who received inhaled xenon and temperature management showed less reduction in brain gray matter volume, especially in areas like the amygdala and temporal gyrus, compared to those who received only temperature management.
- The results suggest that inhaled xenon can help preserve brain structure in this patient group, highlighting its potential therapeutic benefits.
Article Synopsis
- The study examined the link between heavy alcohol use and young-onset cryptogenic ischemic stroke (CIS) in individuals aged 18-49.
- Patients showed significantly higher rates of heavy drinking compared to stroke-free controls, with 13.7% of CIS patients classified as heavy alcohol users versus 6.7% of controls.
- The findings suggest that heavy alcohol consumption, especially binge drinking, is an independent risk factor for CIS in young men, but not in women.
Article Synopsis
- This study investigates the effects of inhaled xenon on metabolic outcomes in out-of-hospital cardiac arrest survivors receiving targeted temperature management.
- Blood samples showed that increased lactate and decreased branched-chain amino acids (BCAAs) were associated with higher mortality rates at 24 and 72 hours post-arrest.
- The findings suggest that high levels of lactate and alanine, along with low BCAAs and small HDL cholesterol, are linked to negative outcomes, while inhaled xenon did not significantly impact the metabolic profile of patients.
Article Synopsis
- Patients with acute intracerebral hemorrhage who were on factor Xa inhibitors were studied to evaluate the effectiveness of andexanet alfa in reversing hematoma expansion compared to usual care.
- In a clinical trial, 263 patients received andexanet while 267 received standard treatment, focusing on hemostatic efficacy and safety outcomes.
- Results showed that andexanet significantly improved hemostatic efficacy (67% vs. 53%) and substantially reduced anti-factor Xa activity, but also led to more thrombotic events (10.3% vs. 5.6% in usual care).