Objectives: Non-adherence to medication is common in the adult ADHD clinical group. The goal of this pre-registered study was to examine whether the DSM-5 Alternative Model of Personality Disorder (AMPD), generality personality dysfunction (LPFS-BF 2.0) or maladaptive personality traits (PID-5), can predict time to premature discontinuation of pharmacological treatment beyond other known factors.
View Article and Find Full Text PDFBackground: Childhood adversity has been associated with increased peripheral inflammation in adulthood. However, not all individuals who experience early adversity develop these inflammatory outcomes. Separately, there is also a link between various internalizing emotional distress conditions (e.
View Article and Find Full Text PDFThe precise control of complex reactions is critical for biological processes, yet our inability to design for specific outcomes limits the development of synthetic analogs. Here, we leverage differentiable simulators to design nontrivial reaction pathways in colloidal assemblies. By optimizing over external structures, we achieve controlled disassembly and particle release from colloidal shells.
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