Publications by authors named "R P Juster"
Objectives In 2008, the National Institute of Mental Health (NIMH) published its strategic plan to structure future research aims and objectives including the development of a new method of classifying mental health disorders. This strategic plan gave rise to the Research Domain Criteria (RDoC) project, a framework aimed at establishing major functional domains of the human psyche ranging from normal to pathological. The Signature Consortium was created in 2009 to develop a data bank capable of contributing to the development of RDoC by identifying profiles, or Signatures, of a psychiatric population, collecting biological, psychosocial, and clinical indicators at critical moments in the care and follow-up of patients visiting the care structures of the Institut universitaire en santé mentale de Montréal (IUSMM).
View Article and Find Full Text PDFSex differences and antidepressant use are not systematically accounted for in studies measuring physiological dysregulations associated with chronic stress and allostatic load (AL) in neuropsychiatry. Critically, assessing commonly prescribed antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and selective serotonin and norepinephrine reuptake inhibitors (SNRIs) could help monitor potential iatrogenic effects on AL and health that are associated with prolonged antidepressant use. The objective of this exploratory analysis was to investigate how male and female psychiatric outpatients using either SSRIs or SNRIs differ in their AL indices.
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- Health is influenced by mitochondrial energy transformation, which plays a crucial role in regulating various body systems that relate to resilience and disease risk throughout life.
- The MiSBIE study aims to explore how mitochondria affect interconnected systems like neuroendocrine, immune, and cognitive functions, focusing on individuals with mitochondrial diseases.
- This research seeks to enhance understanding of mitochondrial diseases, develop new health biomarkers, and better integrate knowledge of the connections between energy processes and overall health.
Article Synopsis
- Cardiovascular disease is a major health issue for transgender women with HIV, partly influenced by factors like hormone therapy and psychosocial stress.
- A study analyzed data from 108 Black and Latina transgender women with HIV to investigate how stress affects CVD risk in relation to hormone therapy duration.
- Findings showed that while hormone therapy duration was linked to higher CVD risk, stress did not significantly impact this relationship, suggesting that age and overall physiological stress (measured by allostatic load) are more critical to CVD risk in this population.