Publications by authors named "R P Groenendijk"

Purpose: Despite recent treatment advances, esophageal cancer still has poor survival and a high morbidity. Exploratory evidence suggests that exercise can reduce cancer-related mortality and recurrence rates. Here, we investigated the effects of an exercise intervention in the first year after esophagectomy on survival in participants of the Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) trial.

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Article Synopsis
  • This study investigated how different grades of tumor response (TRG) and a new scoring system (TRG-ypN) relate to cancer recurrence and survival in patients with esophageal adenocarcinoma after treatment.
  • The research, which included 2,746 patients treated between 2007 and 2016, found that lower TRG scores corresponded to lower recurrence rates and longer overall survival, with TRG1 patients having better outcomes than those with higher scores.
  • Additionally, residual nodal disease had a more significant negative impact on prognosis compared to remaining disease at the primary tumor site, highlighting the importance of nodal status in treatment outcomes.
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This paper provides a definition of back-propagation through geometric correspondences for morphological neural networks. In addition, dilation layers are shown to learn probe geometry by erosion of layer inputs and outputs. A proof-of-principle is provided, in which predictions and convergence of morphological networks significantly outperform convolutional networks.

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Objective: This study investigated the patterns, predictors, and survival of recurrent disease following esophageal cancer surgery.

Background: Survival of recurrent esophageal cancer is usually poor, with limited prospects of remission.

Methods: This nationwide cohort study included patients with distal esophageal and gastroesophageal junction adenocarcinoma and squamous cell carcinoma after curatively intended esophagectomy in 2007 to 2016 (follow-up until January 2020).

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