Comparison of Partially Denatured Cytochrome Structural Ensembles in Solution and Gas Phases Using Cross-Linking Mass Spectrometry.

Electrospray ionization mass spectrometry (ESI-MS) can retain intact protein structures, but details about partially folded and unfolded protein structures during and after introduction to the gas phase are elusive. Here we use ESI-MS with chemical cross-linkers to compare denatured cytochrome structures in both solution and gas phases. Solution phase cross-linking prior to ESI captures solution phase structures, while gas phase cross-linking through ion/ion reactions in the trap cell captures gas phase structures.

Human Needs in Relation to Home Attachment: Towards a Theoretical Framework to Architectural Affordances in Temporary Accommodation to Aid Designers.

The current and rising provision of temporary accommodation in the UK does not always meet the needs of residents with one such contributing factor being the often-poor atmospheric qualities within these environments. Temporary accommodation is a broad term for housing provided for those who have previously been homeless, covering different variations of support or tenancy length. Our research synthesises transdisciplinary literature to create a theoretical framework which can be used to inform the design of suitable temporary accommodation by connecting psychological theories in a novel way to shed light on the parameters of the phenomenon of home attachment, specifically physical, architectural elements.

TIMESS a power analysis tool to estimate the number of locations and repeated measurements for seasonally and clustered mosquito surveys.

Every day, hundreds of mosquito surveys are carried out around the world to inform policy and management decisions on how best to reduce or prevent the burden of mosquito-borne disease or mosquito nuisance. These surveys are usually time consuming and expensive. Mosquito surveillance is the essential component of vector management and control.

Barriers to correct pronoun usage in healthcare settings.

Background: Using correct pronouns is an impactful way to establish affirming environments for transgender and nonbinary (TGNB) patients. However, physicians often report struggling with this.

Objective: This study set out to conduct an initial root cause analysis of factors contributing to medical students and physicians failing to use TGNB patients' correct pronouns.