Publications by authors named "R P Buyalos"
Economic Burden of Endometrial Cancer Associated With Polycystic Ovary Syndrome.
J Clin Endocrinol Metab
December 2024
Context: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged females, and women with PCOS are at increased risk for endometrial cancer (EndoCA), the most common gynecological malignancy.
Objective: Our study sought to assess the economic burden associated with EndoCA in PCOS.
Method: Using PRISMA systematic review guidelines, we evaluated studies on EndoCA rates in patients with PCOS.
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a common condition affecting women's reproductive and metabolic health, and its relationship with global obesity rates is unclear.
- A systematic review analyzed data from 58 studies involving nearly 86,000 adults to explore this connection, finding a borderline association between PCOS and obesity, especially when applying certain diagnostic criteria.
- The research suggests that a rise in obesity rates correlates with an increase in PCOS prevalence, highlighting the need for more high-quality studies to better understand this association.
Objective: To determine whether alterations in nonesterified fatty acid (NEFA) dynamics or degree of hyperandrogenism (HA) contribute to the difference in insulin sensitivity between women with metabolically healthy obese polycystic ovary syndrome (PCOS) (MHO-PCOS) and women with metabolically unhealthy obese PCOS (MUO-PCOS).
Design: Prospective cross-sectional study.
Setting: Tertiary-care academic center.
Background: Polycystic ovary syndrome (PCOS) is the most common hormone disorder affecting about one in seven reproductive-aged women worldwide and approximately 6 million women in the United States (U.S.).
View Article and Find Full Text PDFPurpose: To evaluate the relationship between progesterone and oocyte maturity rate via estradiol to progesterone ratio (E/P) at the time of ovulatory trigger.
Methods: This is a retrospective cohort study of first autologous IVF cycles from January to December 2018 from a private practice fertility center. Serum estradiol and progesterone levels were measured on the day of ovulatory trigger.