Publications by authors named "R P Bertola"
Article Synopsis
- The systematic literature review aimed to analyze the effects of approved biological and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) on the synovial membrane in psoriatic arthritis (PsA) patients and explore potential biomarkers for treatment response.
- A comprehensive search through various databases led to the inclusion of 22 studies, with the majority focusing on the effects of TNF inhibitors and using immunohistochemistry as the primary method for analysis.
- The meta-analysis revealed a significant decrease in CD3+ lymphocytes and CD68+ macrophages in patients treated with bDMARDs, with the reduction in CD3+ cells correlating with clinical response, highlighting its potential as a reliable biomarker
Purpose: To characterize the incidence, timing, and predictors of augmented renal clearance (ARC) in patients with traumatic brain injury (TBI).
Materials And Methods: In 61 patients with TBI, creatinine clearance (CrCl) was prospectively measured from urine samples, over seven days. ARC was defined as a CrCl >130 mL/min/1.
PP098. Lipidic fingerprinting in women with early-onset preeclampsia: A first look.
Pregnancy Hypertens
July 2012
Introduction: preeclampsia is characterized by intense inflammatory response and an anti-angiogenic state. Maternal obesity has been considered to have important impact on the genesis of preeclampsia as lipotoxicity leads to maternal endothelial dysfunction and chronic inflammation. Here we investigate the plasma lipid profile of preeclamptic women.
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